Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-8003
Gene Name: atlastin GTPase 1
Gene Symbol: atl1
Previous Names: fj46c01, wu:fj46c01
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from Fassier et al., 2010
Wild-type Stages, Structures: Blastula:High (3.33h-3.66h) to Hatching:Long-pec (48.0h-60.0h)
  brain, primary motor neuron, spinal cord neural tube motor neuron, whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: sa95
Knockdown reagents: MO1-atl1 (1), MO2-atl1 (1), MO3-atl1 (1)
PHENOTYPE
Data: 3 figures from Fassier et al., 2010
Observed in: cerebellum, motor neuron axon guidance, multicellular organismal locomotion, peripheral neuron (all 7) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Neuropathy, hereditary sensory, type ID 613708
Spastic paraplegia 3A, autosomal dominant 182600
GENE ONTOLOGY
Ontology GO Term
Biological Process determination of dorsal identity (more)
Cellular Component late endosome (more)
Molecular Function GTP binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003191 (1)
  • InterPro:IPR015894 (1)
  • InterPro:IPR027417 (1)
  • Pfam:PF02263 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atl1-001 (1) 2156
    atl1-002 (1) 407
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-atl1 (1)
    CONSTRUCTS WITH SEQUENCES FROM atl1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atl1 Contained in: [BAC] CH211-282C13 (1) (order this)
    atl1 Encodes: [EST] fj46c01
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145700 (1) 2156 bp
    Genomic GenBank:BX936452 (1) 136110 bp
    Select Tool
    Polypeptide UniProtKB:E9QGX9 (1) 559 aa
    Sequence Clusters UniGene:81075 (1)
    Sequence Information (all 12)
    OTHER atl1 GENE PAGES
  • Gene:571909 (1)
  • VEGA:OTTDARG00000029612 (1)
  • Ensembl(Zv9):ENSDARG00000060481 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atl1 13  
    Human ATL1 14 (14q22.1)
  • OMIM:606439
  • Gene:51062
  • Mouse Atl1 12 ( 28.94 cM)
  • MGI:1921241
  • Gene:73991
  • Orthology Details
    CITATIONS (10)