ZFIN ID: ZDB-GENE-030131-8003
Gene Name: atlastin GTPase 1
Gene Symbol: atl1
Previous Names: fj46c01, wu:fj46c01
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from Fassier et al., 2010
Wild-type Stages, Structures: Blastula:High (3.33h-3.66h) to Hatching:Long-pec (48.0h-60.0h)
  brain, primary motor neuron, spinal cord neural tube motor neuron, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa95 Point Mutation ENU
Targeting reagents: MO1-atl1 (1), MO2-atl1 (1), MO3-atl1 (1)
PHENOTYPE
Data: 3 figures from Fassier et al., 2010
Observed in: cerebellum, motor neuron axon guidance, multicellular organismal locomotion, peripheral neuron (all 7) expand
DISEASE ASSOCIATED WITH atl1 HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
hereditary sensory neuropathy Neuropathy, hereditary sensory, type ID 613708
hereditary spastic paraplegia Spastic paraplegia 3A, autosomal dominant 182600
GENE ONTOLOGY 
Ontology GO Term
Biological Process determination of dorsal identity (more)
Cellular Component late endosome (more)
Molecular Function GTP binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003191 (1)
  • InterPro:IPR015894 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR030386 (1)
  • PROSITE:PS51715 (1)
  • Pfam:PF02263 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atl1-001 (1) 2156
    atl1-002 (1) 407
    GENE PRODUCT DESCRIPTION
    ANTIBODIES 
    Ab1-atl1 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atl1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    atl1Contained in: [BAC] CH211-282C13 (1) (order this)
    atl1Encodes: [EST] fj46c01
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145700 (1) 2156bp
    Genomic GenBank:BX936452 (1) 136110bp
    Select Tool
    Polypeptide UniProtKB:E9QGX9 (1) 559aa
    Sequence Clusters UniGene:81075 (1)
    Sequence Information (all 12)
    OTHER atl1 GENE PAGES 
  • Gene:571909 (1)
  • VEGA:OTTDARG00000029612 (1)
  • Ensembl(GRCz10):ENSDARG00000060481 (1)
  • ORTHOLOGY for atl1 (Chr: 13) 
    Species Symbol Chromosome Accession # Evidence
    Human ATL1 14
  • Gene:51062
  • OMIM:606439
  • HGNC:11231
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Mouse Atl1 12
  • MGI:1921241
  • Gene:73991
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (13)