Gene

cd59

ID
ZDB-GENE-030131-7871
Name
CD59 molecule (CD59 blood group)
Symbol
cd59 Nomenclature History
Previous Names
  • fj38b04
  • lndc1
  • ly6/neurotoxin like
  • wu:fj38b04
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits lipopolysaccharide binding activity and lipoteichoic acid binding activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Localizes to membrane. Is expressed in several structures, including blood; central nervous system; hypochord; ovary; and unfertilized egg. Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian cancer. Orthologous to human CD59 (CD59 molecule (CD59 blood group)).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cd59 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy 612300
Associated With cd59 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR016054 Ly-6 antigen/uPA receptor-like
Domain Details Per Protein
Protein Length Ly-6 antigen/uPA receptor-like
UniProtKB:A0A0B5JW41 92
UniProtKB:E7F2M5 118
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cd59 polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations