ZFIN ID: ZDB-GENE-030131-779
Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
Gene Symbol: ywhae1    Nomenclature History

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Previous Names: ywhae, 14-3-3 epsilon (1), fe38c12, wu:fb48f06, wu:fe38c12 (1), wu:fi22e10, zgc:55377, zgc:77062

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have monooxygenase activity and protein domain specific binding activity. Predicted to be involved in oxidation-reduction process. Is expressed in several structures, including immature eye; nervous system; otic vesicle; post-vent region; and tail bud. Orthologous to human YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon).
Genome Resources: Alliance (1),  Gene:322060 (1),  Ensembl(GRCz11):ENSDARG00000006399 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019253Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf387Et Transgenic Insertion Unknown Unknown DNA
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ywhae1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ywhae1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Molecular Function monooxygenase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR023409 14-3-3 protein, conserved site
    Domain IPR023410 14-3-3 domain
    Family IPR000308 14-3-3 protein
    Homologous_superfamily IPR036815 14-3-3 domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ywhae1-201 (1)    Ensembl 1777
    ywhae1-202 (1)    Ensembl 755
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-ywhae1 polyclonal Rabbit WB Millipore
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ywhae1 No data available
    MARKER RELATIONSHIPS
    ywhae1 Contained in: [BAC] DKEY-151P21 (1) (order this)
    ywhae1 Encodes: [EST] fb48f06, fe38c12, fi22e10 (1)
    [cDNA] MGC:55377 (1), MGC:77062 (1), MGC:172188 (1), MGC:192298 (1)
    ywhae1 Has Artifact: [EST] fc64c05
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212605 (1) 1774 nt
    Genomic GenBank:CR524483 (1) 210342 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q7ZW20 (1) 255 aa
    Sequence Information (all 28)
    ORTHOLOGY for ywhae1 ( Chr: 15 )
    CITATIONS (33)