ZFIN ID: ZDB-GENE-030131-7570
Gene Name: regulator of G protein signaling 5a
Gene Symbol: rgs5a    Nomenclature History

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Previous Names: rgs5, fj30h05, wu:fj30h05, zgc:64006 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Human ortholog(s) of this gene implicated in essential hypertension. Is expressed in bulbus arteriosus; cranial blood vessel; eye; and trunk vasculature. Orthologous to human RGS5 (regulator of G protein signaling 5).
Genome Resources: Alliance (1),  Gene:573765 (1),  Ensembl(GRCz11):ENSDARG00000002644 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17283 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31521 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rgs5a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    essential hypertension Alliance [Blood pressure regulation QTL] 145500
    DISEASE ASSOCIATED WITH rgs5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of GTPase activity (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rgs5a-201 (1)    Ensembl 284
    rgs5a-202 (1)    Ensembl 3124
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rgs5a No data available
    MARKER RELATIONSHIPS
    rgs5a Contained in: [BAC] CH211-232F6 (1), DKEY-39O12 (1) (order this)
    rgs5a Encodes: [EST] fj30h05
    [cDNA] MGC:64006 (1), MGC:174043 (1), MGC:198190 (1), MGC:198196 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199962 (1) 2765 nt
    Genomic RefSeq:NW_018394656 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:Q7T2D3 (1) 182 aa
    Sequence Information (all 28)
    ORTHOLOGY for rgs5a ( Chr: 6 )
    CITATIONS (23)