Gene

ptpn6

ID
ZDB-GENE-030131-7513
Name
protein tyrosine phosphatase non-receptor type 6
Symbol
ptpn6 Nomenclature History
Previous Names
  • fj22f05
  • SHP1 (1)
  • wu:fj22f05 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have protein tyrosine phosphatase activity. Involved in innate immune response. Predicted to localize to cytoplasm. Is expressed in blood island; gill; immune system; and liver. Orthologous to human PTPN6 (protein tyrosine phosphatase non-receptor type 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptpn6 Human Ortholog
No data available
Associated With ptpn6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000242 PTP type protein phosphatase
Domain IPR000387 Tyrosine specific protein phosphatases domain
Domain IPR000980 SH2 domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Family IPR012152 Protein-tyrosine phosphatase, non-receptor type-6, -11
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like Protein-tyrosine phosphatase, non-receptor type-6, -11 PTP type protein phosphatase SH2 domain SH2 domain superfamily Tyrosine specific protein phosphatases domain
UniProtKB:C7U118 224
UniProtKB:E7F3D4 589
UniProtKB:F8W5L5 252
UniProtKB:Q801L1 202
UniProtKB:A0A2R8Q2T0 590
UniProtKB:Q803M6 589
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations