Gene

tctn2

ID
ZDB-GENE-030131-751
Name
tectonic family member 2
Symbol
tctn2 Nomenclature History
Previous Names
  • fb44f11
  • si:ch211-89f7.3
  • wu:fb44f11
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Involved in determination of left/right symmetry. Predicted to localize to MKS complex. Human ortholog(s) of this gene implicated in Joubert syndrome 24 and Meckel syndrome 8. Orthologous to human TCTN2 (tectonic family member 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Liu et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tctn2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Joubert syndrome 24 Alliance Joubert syndrome 24 616654
Meckel syndrome 8 Alliance ?Meckel syndrome 8 613885
Associated With tctn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011677 Domain of unknown function DUF1619
Family IPR040354 Tectonic
Domain Details Per Protein
Protein Length Domain of unknown function DUF1619 Tectonic
UniProtKB:F1R5E2 702
UniProtKB:F1Q7Y4 709
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations