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ZIRC
ZFIN ID: ZDB-GENE-030131-7487
Gene Name: angiomotin
Gene Symbol: amot    Nomenclature History

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Previous Names: si:dkey-13f9.6 (1), wu:fj21a07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Involved in angiogenesis; blood vessel endothelial cell migration; and establishment or maintenance of cell polarity. Predicted to localize to the bicellular tight junction and cytoplasmic vesicle. Orthologous to human AMOT (angiomotin).
Genome Resources: Alliance (1),  Gene:563421 (1),  Ensembl(GRCz11):ENSDARG00000078335 (2)
GENE EXPRESSION
All Expression Data: Fig. 6 from Zheng et al., 2009
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022011Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1663 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa3119 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa3123 Point Mutation Unknown Premature Stop ENU
    sa12125 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12810 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16908 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um76 Small Deletion Unknown Splice Site ZINC_FINGER_NUCLEASE
    um77 Insertion Unknown Premature Stop ZINC_FINGER_NUCLEASE
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-amot N/A 5
    MO2-amot N/A 2
    DISEASE ASSOCIATED WITH amot HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH amot VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component bicellular tight junction (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009114 (1)
  • InterPro:IPR024646 (1)
  • Pfam:PF12240 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA amot-202 (1)    Ensembl 2230
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM amot No data available
    MARKER RELATIONSHIPS
    amot Contained in: [BAC] DKEY-13F9 (1) (order this)
    amot Contains: [SNP] rs3729132 (1), rs3729133 (1), rs3729134 (1), rs3729135 (1), rs3729136 (1)
    amot Encodes: [EST] fj21a07
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005173887 (1)
    Genomic GenBank:BX842703 (1) 208780 bp Blast at MegaBLAST
    Polypeptide UniProtKB:E9QFX4 (1) 1009 aa
    Sequence Clusters UniGene:122320 (1)
    Sequence Information (all 18)
    ORTHOLOGY for amot ( Chr: 21 )
    CITATIONS (33)