ZFIN ID: ZDB-GENE-030131-713
Gene Name: non-POU domain containing, octamer-binding
Gene Symbol: nono    Nomenclature History

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Previous Names: wu:fb40d10, wu:fc11d05

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have transcription regulatory region sequence-specific DNA binding activity. Involved in central nervous system development; otic vesicle development; and somite development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 34. Orthologous to human NONO (non-POU domain containing octamer binding).
Genome Resources: Alliance (1),  Gene:321994 (1),  Ensembl(GRCz11):ENSDARG00000020482 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55641]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7143006]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa806 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10208 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20389 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-nono N/A 1
    DISEASE ASSOCIATED WITH nono HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nono VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process central nervous system development (more)
    Cellular Component nucleus (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nono-201 (1)    Ensembl 2298
    nono-202 (1)    Ensembl 879
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nono No data available
    MARKER RELATIONSHIPS
    nono Contained in: [BAC] CH211-202L3 (1), DKEY-103E21 (1) (order this)
    nono Encodes: [EST] fb40d10, fc11d05, IMAGE:7143006 (1)
    [cDNA] MGC:55641 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201579 (1) 1996 nt
    Genomic GenBank:BX470076 (1) 112637 nt
    Select Tool
    Polypeptide UniProtKB:Q802Z5 (1) 441 aa
    Sequence Information (all 19)
    ORTHOLOGY for nono ( Chr: 5 )
    CITATIONS (30)