Gene

setdb2

ID
ZDB-GENE-030131-7093
Name
SET domain bifurcated histone lysine methyltransferase 2
Symbol
setdb2 Nomenclature History
Previous Names
  • wu:fk80d09
Type
protein_coding_gene
Location
Ambiguous Mapping Details/Browsers
Description
Exhibits histone methyltransferase activity (H3-K9 specific). Involved in several processes, including embryonic morphogenesis; histone H3-K9 methylation; and left/right axis specification. Predicted to localize to nucleus. Orthologous to human SETDB2 (SET domain bifurcated histone lysine methyltransferase 2).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With setdb2 Human Ortholog
No data available
Associated With setdb2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001214 SET domain
Domain IPR001739 Methyl-CpG DNA binding
Domain IPR007728 Pre-SET domain
Homologous_superfamily IPR016177 DNA-binding domain superfamily
Domain Details Per Protein
Protein Length DNA-binding domain superfamily Methyl-CpG DNA binding Pre-SET domain SET domain
UniProtKB:E7F7L1 546
UniProtKB:Q06ZW3 551
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-setdb2 polyclonal Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations