ZFIN ID: ZDB-GENE-030131-6664
Gene Name: annexin A1a
Gene Symbol: anxa1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wu:fa01d11, wu:fa05d11, wu:fk69h01

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity; calcium-dependent phospholipid binding activity; and phospholipase A2 inhibitor activity. Involved in fin regeneration. Predicted to localize to cytoplasm; extracellular space; and plasma membrane. Is expressed in eye; integument; muscle; periderm; and yolk syncytial layer. Human ortholog(s) of this gene implicated in brain ischemia and pancreatic cancer. Orthologous to human ANXA1 (annexin A1).
Genome Resources: Alliance (1),  Gene:334724 (1),  Ensembl(GRCz11):ENSDARG00000026726 (2)
GENE EXPRESSION
All Expression Data: 15 figures from 7 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:64000]
Wild-type Stages, Structures: Blastula:Dome (4.33h-4.66h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015618Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33598 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-anxa1a
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH anxa1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH anxa1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fin regeneration (more)
    Cellular Component cytoplasm (more)
    Molecular Function calcium-dependent phospholipid binding (more)
    GO Terms (all 50)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA anxa1a-201 (1)    Ensembl 1208
    anxa1a-202 (1)    Ensembl 1206
    anxa1a-205 (1)    Ensembl 805
    ncRNA anxa1a-002 (1)    Ensembl 603
    anxa1a-004 (1)    Ensembl 814
    anxa1a-006 (1)    Ensembl 555
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-anxa1 polyclonal IgG Rabbit WB Abbiotec
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM anxa1a No data available
    MARKER RELATIONSHIPS
    anxa1a Contained in: [BAC] DKEY-229D2 (1) (order this)
    anxa1a Encodes: [EST] fa01d11, fa05d11, fk69h01
    [cDNA] MGC:64000 (1), MGC:191551 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_181758 (1) 1235 nt
    Genomic GenBank:BX296526 (1) 179086 nt
    Select Tool
    Polypeptide UniProtKB:Q7T3A8 (1) 340 aa
    Sequence Information (all 24)
    ORTHOLOGY for anxa1a ( Chr: 5 )
    CITATIONS (42)