ZFIN ID: ZDB-GENE-030131-6654
Gene Name: tripeptidyl peptidase I
Gene Symbol: tpp1
Sequence Ontology ID : SO:0000704

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Previous Names: cln2, fa01b09, im:7149243, wu:fa01b09

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7149243]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3587 Point Mutation Exon 11 Premature Stop ENU
sa11 Point Mutation Exon 3 Premature Stop ENU
sa2895 Point Mutation Unknown Splice Site ENU
sa6483 Point Mutation Unknown Premature Stop ENU
sa8389 Point Mutation Unknown Premature Stop ENU
Targeting reagents:
PHENOTYPE
Data: 10 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH tpp1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 7 Spinocerebellar ataxia, autosomal recessive 7 609270
neuronal ceroid lipofuscinosis 2 Ceroid lipofuscinosis, neuronal, 2 204500
GENE ONTOLOGY
Ontology GO Term
Biological Process central nervous system development (more)
Molecular Function tripeptidyl-peptidase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000209 (1)
  • InterPro:IPR015366 (1)
  • InterPro:IPR030400 (1)
  • InterPro:IPR036852 (1)
  • PROSITE:PS51695 (1)
  • Pfam:PF00082 (1)
  • Pfam:PF09286 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tpp1-001 (1) 2054
    ncRNA tpp1-002 (1) 735
    mRNA tpp1-003 (1) 868
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tpp1 No data available
    MARKER RELATIONSHIPS
    tpp1Contained in: [BAC] DKEY-230N6 (1) (order this)
    tpp1Encodes: [EST] fa01b09, IMAGE:7149243 (1) (order this)
    [cDNA] MGC:194849 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128798 (1) 1758bp
    Genomic GenBank:BX546455 (1) 62516bp
    Select Tool
    Polypeptide UniProtKB:F8W2M8 (1) 582aa
    Sequence Clusters UniGene:35596 (1)
    Sequence Information (all 17)
    OTHER tpp1 GENE PAGES
  • Alliance (1)
  • Gene:798347 (1)
  • VEGA:OTTDARG00000035050 (1)
  • Ensembl(GRCz10):ENSDARG00000042793 (1)
  • ORTHOLOGY for tpp1 (Chr: 17)
    CITATIONS (27)