ZFIN ID: ZDB-GENE-030131-6606
Gene Name: flavin containing dimethylaniline monoxygenase 5
Gene Symbol: fmo5    Nomenclature History

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Previous Names: sb:cb1007, wu:fc05b01 (1), wu:fk47g04 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have N,N-dimethylaniline monooxygenase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum membrane. Is expressed in several structures, including ectoderm; epidermis; intestinal bulb primordium; presumptive ectoderm; and pronephric duct. Human ortholog(s) of this gene implicated in hypertension; inherited metabolic disorder; and trimethylaminuria. Orthologous to several human genes including FMO5 (flavin containing dimethylaniline monoxygenase 5).
Genome Resources: Alliance (1),  Gene:794311 (1),  Ensembl(GRCz11):ENSDARG00000016357 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17238 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fmo5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fmo5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function flavin adenine dinucleotide binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fmo5-201 (1)    Ensembl 2209
    ncRNA fmo5-202 (1)    Ensembl 888
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fmo5 No data available
    MARKER RELATIONSHIPS
    fmo5 Contained in: [BAC] CH211-191D7 (1), DKEY-239I20 (order this)
    fmo5 Contains: [SNP] rs3729015 (1)
    fmo5 Encodes: [EST] cb1007 (1) (order this), fc05b01, fk47g04
    [cDNA] MGC:65839 (1), MGC:162406 (1), MGC:171397 (1), MGC:174986 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_198910 (1) 2202 nt
    Genomic RefSeq:NW_018395065 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A8KB08 (1) 560 aa
    Sequence Information (all 36)
    ORTHOLOGY for fmo5 ( Chr: 20 )
    CITATIONS (31)