Gene

fn1b

ID
ZDB-GENE-030131-6545
Name
fibronectin 1b
Symbol
fn1b Nomenclature History
Previous Names
  • fn1l
  • fn3 (1)
  • cb1057 (1)
  • wu:fa14f11
  • wu:fb03c02
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have integrin binding activity and proteoglycan binding activity. Involved in atrioventricular valve morphogenesis; heart field specification; and somitogenesis. Predicted to localize to collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including fin; integument; mesoderm; musculature system; and periderm. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis and membranoproliferative glomerulonephritis. Orthologous to human FN1 (fibronectin 1).
Genome Resources
Note
None
Expression
All Expression Data
33 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 7 from Steed et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fn1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Glomerulopathy with fibronectin deposits 2 601894
Spondylometaphyseal dysplasia, corner fracture type 184255
Associated With fn1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000083 Fibronectin, type I
Domain IPR000562 Fibronectin type II domain
Domain IPR003961 Fibronectin type III
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR013806 Kringle-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036943 Fibronectin type II domain superfamily
Domain Details Per Protein
Protein Length Fibronectin, type I Fibronectin type II domain Fibronectin type II domain superfamily Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold Kringle-like fold
UniProtKB:A3KNU0 369
UniProtKB:A2CEW3 2500
UniProtKB:A0A0R4IDI3 2419
UniProtKB:A0A0R4IXY1 287
UniProtKB:Q7T1S2 358
UniProtKB:Q7T2W7 195
UniProtKB:Q6JAN2 2408
UniProtKB:Q58XP5 2500
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations