Gene

ints1

ID
ZDB-GENE-030131-6523
Name
integrator complex subunit 1
Symbol
ints1 Nomenclature History
Previous Names
  • fa14a05
  • wu:fa14a05 (1)
  • wu:fa55a06
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to be involved in U2 snRNA 3'-end processing. Predicted to localize to integrator complex. Is expressed in brain and eye. Used to study cataract and neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Orthologous to human INTS1 (integrator complex subunit 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Krall et al., 2019
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Krall et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ints1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies Alliance Neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies 618571
Associated With ints1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR022145 Domain of unknown function DUF3677
Family IPR038902 Integrator complex subunit 1
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-type fold Domain of unknown function DUF3677 Integrator complex subunit 1
UniProtKB:A0A0R4IJ75 2192
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations