ZFIN ID: ZDB-GENE-030131-6482
Gene Name: STE20 related adaptor alpha
Gene Symbol: strada    Nomenclature History

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Previous Names: fj99g05, wu:fj99g05, zgc:56109

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in activation of protein kinase activity; intracellular signal transduction; and neuron projection morphogenesis. Predicted to localize to the cytoplasm. Orthologous to human STRADA (STE20 related adaptor alpha).
Genome Resources: Alliance (1),  Gene:334550 (1),  Ensembl(GRCz11):ENSDARG00000037929 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56109]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10477 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20047 Point Mutation Unknown Missense, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH strada HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Polyhydramnios, megalencephaly, and symptomatic epilepsy 611087
    DISEASE ASSOCIATED WITH strada VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000719 Protein kinase domain
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA strada-201 (1)    Ensembl 2305
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM strada No data available
    MARKER RELATIONSHIPS
    strada Contained in: [BAC] DKEY-15N1 (1) (order this)
    strada Encodes: [EST] fj99g05
    [cDNA] MGC:56109 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199911 (1) 1968 nt
    Genomic GenBank:BX324157 (1) 272769 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q5T1 (1) 378 aa
    Sequence Information (all 15)
    ORTHOLOGY for strada ( Chr: 3 )
    CITATIONS (19)