Gene

kdm4ab

ID
ZDB-GENE-030131-6279
Name
lysine (K)-specific demethylase 4A, genome duplicate b
Symbol
kdm4ab Nomenclature History
Previous Names
  • jmjd2A (1)
  • jmjd2al
  • si:ch211-262l3.1
  • wu:fi42b08
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Involved in blood vessel morphogenesis. Predicted to localize to histone methyltransferase complex. Human ortholog(s) of this gene implicated in several diseases, including autistic disorder; esophagus squamous cell carcinoma; head and neck cancer; renal cell carcinoma; and withdrawal disorder. Orthologous to several human genes including KDM4A (lysine demethylase 4A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kdm4ab Human Ortholog
No data available
Associated With kdm4ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001965 Zinc finger, PHD-type
Domain IPR002999 Tudor domain
Domain IPR003347 JmjC domain
Domain IPR003349 JmjN domain
Domain IPR034732 Extended PHD (ePHD) domain
Domain IPR040477 Lysine-specific demethylase 4, Tudor domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length Extended PHD (ePHD) domain JmjC domain JmjN domain Lysine-specific demethylase 4, Tudor domain Tudor domain Zinc finger, FYVE/PHD-type Zinc finger, PHD-type Zinc finger, RING/FYVE/PHD-type
UniProtKB:F1QNG0 1045
UniProtKB:Q802U7 895
UniProtKB:A0A2R8QE74 982
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations