Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-6070
Gene Name: nipped-B homolog b (Drosophila)
Gene Symbol: nipblb
Previous Names: nipbl (1), wu:fi33d08 (1)
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from Muto et al., 2011
Wild-type Stages, Structures: Blastula:512-cell (2.75h-3.0h) to Pharyngula:Prim-15 (30.0h-36.0h)
  blastoderm, blastodisc, head, Kupffer's vesicle surrounds (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la027180Tg, sa10463, sa17819
Knockdown reagents: MO1-nipblb (1), MO2-nipblb (1), MO3-nipblb (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Cornelia de Lange syndrome 1 122470
GENE ONTOLOGY
Ontology GO Term
Biological Process digestive tract development (more)
Cellular Component nucleus (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011989 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR024986 (1)
  • InterPro:IPR026003 (1)
  • Pfam:PF12765 (1)
  • Pfam:PF12830 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nipblb-001 (1) 9367
    ncRNA nipblb-002 (1) 753
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-nipblb (1)
    CONSTRUCTS WITH SEQUENCES FROM nipblb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nipblb Contained in: [BAC] CH211-135J7 (1) (order this), DKEY-21N12 (1)
    nipblb Encodes: [EST] fi33d08
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001161447 (1) 9738 bp
    Genomic GenBank:AL929053 (1) 142345 bp
    Select Tool
    Polypeptide UniProtKB:F1QBY1 (1) 2876 aa
    Sequence Clusters UniGene:78039 (1)
    Sequence Information (all 17)
    OTHER nipblb GENE PAGES
  • Gene:794108 (1)
  • VEGA:OTTDARG00000031185 (1)
  • Ensembl(Zv9):ENSDARG00000061052 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish nipblb 10  
    Human NIPBL 5 (5p13.2)
  • OMIM:608667
  • Gene:25836
  • Mouse Nipbl 15 ( 3.82 cM)
  • MGI:1913976
  • Gene:71175
  • Orthology Details
    CITATIONS (17)