ZFIN ID: ZDB-GENE-030131-6070
Gene Name: nipped-B homolog b (Drosophila)
Gene Symbol: nipblb
Previous Names: nipbl (1), wu:fi33d08 (1)
Location: Chr: 10 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Blastula:512-cell (2.75h-3.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
  blastoderm, blastodisc, central nervous system, diencephalon (all 12) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la027180Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10463 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17819 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-nipblb (1), MO2-nipblb (1), MO3-nipblb (1)
    PHENOTYPE
    Data: 3 figures from Pistocchi et al., 2013
    Observed in: apoptotic process, brain, central nervous system development, eye (all 7) expand
    DISEASE ASSOCIATED WITH nipblb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cornelia de Lange syndrome Cornelia de Lange syndrome 1 122470
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process digestive tract development (more)
    Cellular Component nucleus (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011989 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR024986 (1)
  • InterPro:IPR026003 (1)
  • Pfam:PF12765 (1)
  • Pfam:PF12830 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nipblb-001 (1) 9367
    ncRNA nipblb-002 (1) 753
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-nipblb (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nipblb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nipblbContained in: [BAC] CH211-135J7 (1) (order this), DKEY-21N12 (1) (order this)
    nipblbEncodes: [EST] fi33d08
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001161447 (1) 9738bp
    Genomic GenBank:AL929053 (1) 142345bp
    Select Tool
    Polypeptide UniProtKB:F1QBY1 (1) 2876aa
    Sequence Clusters UniGene:78039 (1)
    Sequence Information (all 16)
    OTHER nipblb GENE PAGES
  • Gene:794108 (1)
  • VEGA:OTTDARG00000031185 (1)
  • Ensembl(GRCz10):ENSDARG00000061052 (1)
  • ORTHOLOGY for nipblb (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human NIPBL 5
  • Gene:25836
  • OMIM:608667
  • HGNC:28862
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Mouse Nipbl 15
  • MGI:1913976
  • Gene:71175
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (19)