Gene
tmpoa
- ID
- ZDB-GENE-030131-6003
- Name
- thymopoietin a
- Symbol
- tmpoa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Enables chromatin binding activity. Acts upstream of or within mitotic nuclear membrane reassembly. Located in condensed chromosome and nuclear outer membrane-endoplasmic reticulum membrane network. Orthologous to human TMPO (thymopoietin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55606 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| ct3bGt | Transgenic insertion | Unknown | Unknown | DNA | |
| sa6936 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa11203 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa17619 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa33437 | Allele with one point mutation | Unknown | Splice Site | ENU |
1 - 5 of 5
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | LEM domain | LEM domain-containing | LEM/LEM-like domain superfamily | LEM-like domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q7ZTV0 | InterPro | 657 | ||||
| UniProtKB:A0A8M2BBX9 | InterPro | 557 | ||||
| UniProtKB:A0A8M2BC05 | InterPro | 615 | ||||
| UniProtKB:Q5RGX5 | InterPro | 515 | ||||
| UniProtKB:Q5RGX2 | InterPro | 369 |
1 - 5 of 8 Show all
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-13I19 | ZFIN Curated Data | |
| Contains | SNP | rs3727775 | ZFIN Curated Data | |
| Contains | SNP | rs3727776 | ZFIN Curated Data | |
| Contains | SNP | rs3727777 | ZFIN Curated Data | |
| Contains | SNP | rs3727778 | ZFIN Curated Data | |
| Encodes | EST | fc26f12 | ||
| Encodes | EST | fd21f02 | ZFIN Curated Data | |
| Encodes | EST | fi29h05 | ||
| Encodes | cDNA | MGC:55606 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192948 | ZFIN Curated Data |
1 - 10 of 10
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001328563 (1) | 2587 nt | ||
| Genomic | GenBank:BX649476 (1) | 126315 nt | ||
| Polypeptide | UniProtKB:Q5RGX4 (1) | 685 aa |
- Safian, D., Bogerd, J., Schulz, R.W. (2019) Regulation of spermatogonial development by Fsh: the complementary roles of locally produced Igf and Wnt signaling molecules in adult zebrafish testis. General and comparative endocrinology. 284:113244
- Zada, D., Bronshtein, I., Lerer-Goldshtein, T., Garini, Y., Appelbaum, L. (2019) Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons. Nature communications. 10:895
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Shih, Y.H., Zhang, Y., Ding, Y., Ross, C.A., Li, H., Olson, T.M., Xu, X. (2015) Cardiac Transcriptome and Dilated Cardiomyopathy Genes in Zebrafish. Circulation. Cardiovascular genetics. 8(2):261-9
- Trinh, A., Hochgreb, T., Graham, M., Wu, D., Ruf-Zamojski, F., Jayasena, C.S., Saxena, A., Hawk, R., Gonzalez-Serricchio, A., Dixson, A., Chow, E., Gonzales, C., Leung, H.Y., Solomon, I., Bronner-Fraser, M., Megason, S.G., and Fraser, S.E. (2011) A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes & Development. 25(21):2306-20
- De Wit, M., Keil, D., Remmerie, N., Ven, K.V., Brandhof, E.J., Knapen, D., Witters, E., and Coen, W.D. (2008) Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches. Chemosphere. 74(1):96-105
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Prüfert, K., Winkler, C., Paulin-Levasseur, M., and Krohne, G. (2004) The lamina-associated polypeptide 2 (LAP2) genes of zebrafish and chicken: no LAP2alpha isoform is synthesised by non-mammalian vertebrates. European journal of cell biology. 83(8):403-411
- Schoft, V.K., Beauvais, A.J., Lang, C., Gajewski, A., Prufert, K., Winkler, C., Akimenko, M.-A., Paulin-Levasseur, M., and Krohne, G. (2003) The lamina-associated polypeptide 2 (LAP2) isoforms {beta}, {gamma} and {omega} of zebrafish: developmental expression and behavior during the cell cycle. Journal of Cell Science. 116(12):2505-2517
1 - 10 of 12
Show