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General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-5906
Gene Name: glutamate-cysteine ligase, modifier subunit
Gene Symbol: gclm
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: GLCLR (1), id:ibd3182, wu:fi24c07

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have enzyme regulator activity. Predicted to be involved in glutathione biosynthetic process and positive regulation of glutamate-cysteine ligase activity. Predicted to localize to the  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gclm HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
{Myocardial infarction, susceptibility to} 608446
DISEASE ASSOCIATED WITH gclm VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process glutathione biosynthetic process (more)
Cellular Component glutamate-cysteine ligase complex (more)
Molecular Function glutamate-cysteine ligase catalytic subunit binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR032963 (1)
  • InterPro:IPR036812 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA gclm-002 (1) 525
    mRNA gclm-201 (1) 1826
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gclm No data available
    MARKER RELATIONSHIPS
    gclmContained in: [BAC] DKEY-7O6 (1) (order this)
    gclmContains: [SNP] rs3728145 (1), rs3728146 (1)
    gclmEncodes: [EST] fi24c07, ibd3182 (1) (order this), IMAGE:6907712 (1) (order this)
    [cDNA] MGC:55903 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199845 (1) 1844bp
    Genomic GenBank:BX005425 (1) 252440bp Blast at MegaBLAST
    Polypeptide UniProtKB:A8WHP4 (1) 273aa
    Sequence Clusters UniGene:80559 (1)
    Sequence Information (all 16)
    ORTHOLOGY for gclm (Chr: 8)
    CITATIONS (34)