ZFIN ID: ZDB-GENE-030131-5739
Gene Name: ubiquitin specific peptidase 42
Gene Symbol: usp42    Nomenclature History

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Previous Names: fi15g04, wu:fi15g04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activity and thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in protein deubiquitination and regulation of apoptotic process. Orthologous to several human genes including USP42 (ubiquitin specific peptidase 42).
Genome Resources: Alliance (1),  Gene:327528 (1),  Ensembl(GRCz11):ENSDARG00000077300 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146942]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012129Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018075Tg Transgenic Insertion Unknown Unknown DNA
    sa10774 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35249 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35250 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42004 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-usp42 N/A 1
    DISEASE ASSOCIATED WITH usp42 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH usp42 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein deubiquitination (more)
    Molecular Function cysteine-type peptidase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR018200 Ubiquitin specific protease, conserved site
    Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    Domain IPR028889 Ubiquitin specific protease domain
    Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA usp42-201 (1)    Ensembl 4246
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM usp42 No data available
    MARKER RELATIONSHIPS
    usp42 Contained in: [BAC] DKEY-13J5 (order this), DKEY-33F9 (order this)
    usp42 Encodes: [EST] fi15g04, IMAGE:7146942 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005169463 (1)
    Genomic GenBank:CR932017 (1) 165406 nt
    Select Tool
    Polypeptide UniProtKB:F1QY38 (1) 1168 aa
    Sequence Information (all 25)
    ORTHOLOGY for usp42 ( Chr: 12 )
    CITATIONS (26)