Gene

hsd17b12a

ID
ZDB-GENE-030131-5628
Name
hydroxysteroid (17-beta) dehydrogenase 12a
Symbol
hsd17b12a Nomenclature History
Previous Names
  • fi06g11
  • zf 3.1 (1)
  • wu:fi06g11
  • zgc:55589
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable estradiol 17-beta-dehydrogenase activity. Predicted to be involved in estrogen biosynthetic process and fatty acid biosynthetic process. Predicted to act upstream of or within steroid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in several structures, including EVL; digestive system; integument; nervous system; and pleuroperitoneal region. Orthologous to human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hsd17b12a Human Ortholog
No data available
Associated With hsd17b12a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR
UniProtKB:Q6P3L6 319
UniProtKB:B2GPH2 319
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations