Gene

taf1

ID
ZDB-GENE-030131-5576
Name
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Symbol
taf1 Nomenclature History
Previous Names
  • wu:fi04f03
  • wu:fy39f07
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Involved in developmental growth and midbrain development. Predicted to localize to transcription factor TFIID complex. Human ortholog(s) of this gene implicated in X-linked dystonia-parkinsonism and syndromic X-linked intellectual disability. Orthologous to several human genes including TAF1 (TATA-box binding protein associated factor 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With taf1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked dystonia-parkinsonism Alliance Dystonia-Parkinsonism, X-linked 314250
Mental retardation, X-linked, syndromic 33 300966
Associated With taf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018359 Bromodomain, conserved site
Domain IPR001487 Bromodomain
Domain IPR009067 TAFII-230 TBP-binding
Domain IPR022591 Transcription initiation factor TFIID subunit 1, domain of unknown function
Domain IPR041670 Zinc knuckle
Family IPR011177 Transcription initiation factor TFIID subunit 1, animal
Family IPR040240 Transcription initiation factor TFIID subunit 1
Homologous_superfamily IPR036427 Bromodomain-like superfamily
Homologous_superfamily IPR036741 TAFII-230 TBP-binding domain superfamily
Domain Details Per Protein
Protein Length Bromodomain Bromodomain, conserved site Bromodomain-like superfamily TAFII-230 TBP-binding TAFII-230 TBP-binding domain superfamily Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 1, animal Transcription initiation factor TFIID subunit 1, domain of unknown function Zinc knuckle
UniProtKB:Q504C9 583
UniProtKB:Q0V949 583
UniProtKB:Q6DEL4 587
UniProtKB:A1L212 583
UniProtKB:A5PL52 368
UniProtKB:Q4V9A6 583
UniProtKB:Q1LYC2 1947
UniProtKB:Q4KM19 583
UniProtKB:Q1JQ12 583
UniProtKB:F1R1I4 368
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations