ZFIN ID: ZDB-GENE-030131-5576
Gene Name: TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene Symbol: taf1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wu:fi04f03, wu:fy39f07

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have TBP-class protein binding activity; histone acetyltransferase activity; and sequence-specific DNA binding activity. Involved in developmental growth and midbrain development. Predicted to localize to transcription factor TFIID complex. Human ortholog(s) of this gene implicated in X-linked dystonia-parkinsonism and syndromic X-linked intellectual disability. Orthologous to several human genes including TAF1 (TATA-box binding protein associated factor 1).
Genome Resources: Alliance (1),  Gene:555452 (1),  Ensembl(GRCz11):ENSDARG00000035330 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6898986]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029096Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1937 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10523 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15367 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20475 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20476 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33651 Point Mutation Unknown Premature Stop ENU
    sa40495 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40496 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40497 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40498 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40499 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • uu1931 Small Deletion Unknown Unknown CRISPR
    uu1941 Small Deletion Exon 8 Frameshift, Premature Stop CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-taf1
    1
    CRISPR2-taf1 1
    CRISPR3-taf1 1
    MO1-taf1 N/A 1
    MO2-taf1 N/A 1
    DISEASE ASSOCIATED WITH taf1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    X-linked dystonia-parkinsonism Alliance Dystonia-Parkinsonism, X-linked 314250
    Mental retardation, X-linked, syndromic 33 300966
    DISEASE ASSOCIATED WITH taf1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process developmental growth (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA taf1-201 (1)    Ensembl 6220
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM taf1 No data available
    MARKER RELATIONSHIPS
    taf1 Contained in: [BAC] CH211-222C22 (1)
    taf1 Encodes: [EST] fi04f03, fy39f07, IMAGE:6898986
    [cDNA] MGC:165365 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044785 (1) 6220 nt
    Genomic GenBank:BX005407 (1) 209796 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LYC2 (1) 1947 aa
    Sequence Information (all 52)
    ORTHOLOGY for taf1 ( Chr: 5 )
    CITATIONS (35)