Gene

keap1a

ID
ZDB-GENE-030131-556
Name
kelch-like ECH-associated protein 1a
Symbol
keap1a Nomenclature History
Previous Names
  • keap1
  • klhl19 (1)
  • wu:fb36f11 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Involved in cellular protein metabolic process; cellular response to prostaglandin stimulus; and cellular response to xenobiotic stimulus. Predicted to localize to cytoplasm and inclusion body. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in gallbladder cancer. Orthologous to human KEAP1 (kelch like ECH associated protein 1).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With keap1a Human Ortholog
No data available
Associated With keap1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR011705 BTB/Kelch-associated
Family IPR017096 BTB-kelch protein
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR015915 Kelch-type beta propeller
Repeat IPR006652 Kelch repeat type 1
Domain Details Per Protein
Protein Length BTB/Kelch-associated BTB-kelch protein BTB/POZ domain Kelch repeat type 1 Kelch-type beta propeller SKP1/BTB/POZ domain superfamily
UniProtKB:Q1ECZ2 601
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations