Gene

castor2

ID
ZDB-GENE-030131-5505
Name
cytosolic arginine sensor for mTORC1 subunit 2
Symbol
castor2 Nomenclature History
Previous Names
  • gats
  • gatsl2
  • sb:cb509
  • wu:fc27d10
  • wu:fd20f09
  • wu:fe01c02
  • zgc:55700
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to be involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Predicted to colocalize with GATOR2 complex. Is expressed in artery; blood; notochord; and yolk syncytial layer. Orthologous to several human genes including CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With castor2 Human Ortholog
No data available
Associated With castor2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR027795 CASTOR, ACT domain
Domain IPR040778 CASTOR1, N-terminal
Family IPR026249 CASTOR family
Homologous_superfamily IPR045865 ACT-like domain
Domain Details Per Protein
Protein Length ACT-like domain CASTOR1, N-terminal CASTOR, ACT domain CASTOR family
UniProtKB:Q7ZVS6 329
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations