Gene

hyou1

ID
ZDB-GENE-030131-5344
Name
hypoxia up-regulated 1
Symbol
hyou1 Nomenclature History
Previous Names
  • id:ibd5056
  • wu:fd14c05
  • zgc:56019
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable ATP binding activity. Predicted to be involved in cellular response to hypoxia and negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. Predicted to be located in endoplasmic reticulum lumen. Predicted to be part of endoplasmic reticulum chaperone complex. Is expressed in several structures, including anterior axial hypoblast; digestive system; hatching gland; immature eye; and polster. Human ortholog(s) of this gene implicated in immunodeficiency 59. Orthologous to human HYOU1 (hypoxia up-regulated 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hyou1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 59 Alliance ?Immunodeficiency 59 and hypoglycemia 233600
Associated With hyou1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018181 Heat shock protein 70, conserved site
Family IPR013126 Heat shock protein 70 family
Homologous_superfamily IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily
Homologous_superfamily IPR029048 Heat shock protein 70kD, C-terminal domain superfamily
Homologous_superfamily IPR043129 ATPase, nucleotide binding domain
Domain Details Per Protein
Protein Length ATPase, nucleotide binding domain Heat shock protein 70, conserved site Heat shock protein 70 family Heat shock protein 70kD, C-terminal domain superfamily Heat shock protein 70kD, peptide-binding domain superfamily
UniProtKB:A0A2R8QLL5 1003
UniProtKB:Q7ZUW2 980
UniProtKB:F1QUW4 980
UniProtKB:B2GRZ4 980
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations