Gene

lrwd1

ID

ZDB-GENE-030131-5335

Name

leucine-rich repeats and WD repeat domain containing 1

Symbol

lrwd1 Nomenclature History

Previous Names

si:dkey-261j4.9
wu:fb78b03
wu:ft31b04

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity; methyl-CpG binding activity; and methylated histone binding activity. Predicted to be involved in chromatin organization and establishment of protein localization to chromatin. Predicted to localize to kinetochore; nuclear origin of replication recognition complex; and pericentric heterochromatin. Is expressed in blastomere. Orthologous to human LRWD1 (leucine rich repeats and WD repeat domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu407 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrwd1 Human Ortholog

No data available

Associated With lrwd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR001680	WD40 repeat
Repeat	IPR025875	Leucine rich repeat 4

Domain Details Per Protein

Protein	Length	Leucine-rich repeat	Leucine rich repeat 4	Leucine-rich repeat domain superfamily	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A0R4IKV7 InterPro	768
UniProtKB:B0R160 InterPro	763
UniProtKB:A0JMB5 InterPro	528

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	lrwd1-201 (1) Ensembl	2660 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	lrwd1-002 (1) Ensembl	665 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations