ZFIN ID: ZDB-GENE-030131-5275
Gene Name: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Gene Symbol: slc25a4
Previous Names: fa22e07, wu:fa22e07, zgc:77591
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (11 images) from Thisse et al., 2004 [MGC:77591]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  cephalic musculature, hypaxial myotome region, musculature system, myotome (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa12193 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc25a4 HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 2 609283
    Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 2 609283
    Mitochondrial DNA depletion syndrome 12 (cardiomyopathic type) 615418
    Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 2 609283
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transporter activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002067 (1)
  • InterPro:IPR002113 (1)
  • InterPro:IPR018108 (1)
  • InterPro:IPR023395 (1)
  • PROSITE:PS50920 (1)
  • Pfam:PF00153 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc25a4-001 (1) 1434
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc25a4 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    slc25a4Contained in: [BAC] DKEY-256E7 (1) (order this)
    slc25a4Encodes: [EST] fa22e07
    [cDNA] MGC:77591 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_214702 (1) 1475bp
    Genomic GenBank:CR759951 (1) 120721bp
    Select Tool
    Polypeptide UniProtKB:Q6NX10 (1) 298aa
    Sequence Clusters UniGene:75854 (1)
    Sequence Information (all 10)
    OTHER slc25a4 GENE PAGES 
  • Gene:327067 (1)
  • VEGA:OTTDARG00000021642 (1)
  • Ensembl(GRCz10):ENSDARG00000027355 (1)
  • ORTHOLOGY for slc25a4 (Chr: 1) 
    Species Symbol Chromosome Accession # Evidence
    Human SLC25A4 4
  • Gene:291
  • OMIM:103220
  • HGNC:10990
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (19)