Gene

eif2s1a

ID
ZDB-GENE-030131-526
Name
eukaryotic translation initiation factor 2, subunit 1 alpha a
Symbol
eif2s1a Nomenclature History
Previous Names
  • eif2s1l
  • fb36a08
  • wu:fb36a08 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have ribosome binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to localize to several cellular components, including eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 2 complex; and eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif2s1a Human Ortholog
No data available
Associated With eif2s1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003029 S1 domain
Domain IPR022967 RNA-binding domain, S1
Family IPR011488 Translation initiation factor 2, alpha subunit
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily
Homologous_superfamily IPR024055 Translation initiation factor 2, alpha subunit, C-terminal
Domain Details Per Protein
Protein Length Nucleic acid-binding, OB-fold RNA-binding domain, S1 S1 domain Translation initiation factor 2, alpha subunit Translation initiation factor 2, alpha subunit, C-terminal Translation initiation factor 2, alpha subunit, middle domain superfamily
UniProtKB:Q7ZWD3 315
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations