ZFIN ID: ZDB-GENE-030131-526
Gene Name: eukaryotic translation initiation factor 2, subunit 1 alpha a
Gene Symbol: eif2s1a    Nomenclature History

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Previous Names: eif2s1l, fb36a08, wu:fb36a08 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have ribosome binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to localize to several cellular components, including eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 2 complex; and eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha).
Genome Resources: Alliance (1),  Gene:321807 (1),  Ensembl(GRCz11):ENSDARG00000005827 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56510]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH eif2s1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH eif2s1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process translation (more)
Cellular Component cytoplasm (more)
Molecular Function nucleic acid binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA eif2s1a-201 (1)    Ensembl 1523
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM eif2s1a No data available
MARKER RELATIONSHIPS
eif2s1a Contained in: [BAC] CH211-37L23 (1)
eif2s1a Encodes: [EST] fb36a08
[cDNA] MGC:56510 (1), MGC:77143 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_199569 (1) 1539 nt
Genomic GenBank:BX679675 (1) 119154 nt
Select Tool
Polypeptide UniProtKB:Q7ZWD3 (1) 315 aa
Sequence Information (all 14)
ORTHOLOGY for eif2s1a ( Chr: 17 )
CITATIONS (33)