ZFIN ID: ZDB-GENE-030131-4869
Gene Name: glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
Gene Symbol: gpd2    Nomenclature History

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Previous Names: cb853 (1), im:7147983, mGPDH (1), wu:fe02f02, zgc:153729

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and glycerol-3-phosphate dehydrogenase (quinone) activity. Predicted to be involved in glycerol-3-phosphate metabolic process and oxidation-reduction process. Predicted to localize to mitochondrion. Is expressed in several structures, including adaxial cell; ectoderm; musculature system; pectoral fin bud; and peripheral olfactory organ. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2).
Genome Resources: Alliance (1),  Gene:751628 (1),  Ensembl(GRCz11):ENSDARG00000062430 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025358Tg Transgenic Insertion Unknown Unknown DNA
sa7579 Point Mutation Unknown Missense ENU
sa9425 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17515 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33826 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45245 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gpd2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    type 2 diabetes mellitus Alliance {Diabetes, type 2, susceptibility to} 125853
    DISEASE ASSOCIATED WITH gpd2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glycerol-3-phosphate metabolic process (more)
    Cellular Component glycerol-3-phosphate dehydrogenase complex (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gpd2-203 (1)    Ensembl 2668
    ncRNA gpd2-002 (1)    Ensembl 1671
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gpd2 No data available
    MARKER RELATIONSHIPS
    gpd2 Contained in: [BAC] CH211-199N13 (1), DKEY-287B3 (1) (order this)
    gpd2 Encodes: [EST] cb853 (1) (order this), fe02f02, IMAGE:7147983 (1)
    [cDNA] MGC:153729 (1), MGC:192462 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045348 (1) 2140 nt
    Genomic GenBank:CR854986 (1) 156618 nt
    Select Tool
    Polypeptide UniProtKB:F1Q555 (1) 726 aa
    Sequence Information (all 25)
    ORTHOLOGY for gpd2 ( Chr: 6 )
    CITATIONS (24)