ZFIN ID: ZDB-GENE-030131-482 |
Gene Name: | AKT1 substrate 1 (proline-rich) | ||||||
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Gene Symbol: | akt1s1 Nomenclature History | ||||||
Previous Name: | wu:fb34a04 | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 3 Mapping Details/Browsers | ||||||
Description: | Predicted to be involved in negative regulation of TOR signaling and negative regulation of protein kinase activity. Predicted to localize to the TORC1 complex and cytoplasm. Is expressed in eye. Orthologous to human AKT1S1 (AKT1 substrate 1). | ||||||
Genome Resources: | Alliance (1), Gene:566559 (1), Ensembl(GRCz11):ENSDARG00000074667 (2) |
All Expression Data: | Fig. 1 from Sasore et al., 2014 |
Wild-type Stages, Structures: | Gastrula:Shield (6.0h-8.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) |
Curated Microarray Expression: | GEO (1) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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sa33194 | Point Mutation | Unknown | Premature Stop | ENU |
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sa40083 | Point Mutation | Unknown | Premature Stop | ENU |
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Ontology | GO Term |
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Biological Process | negative regulation of TOR signaling (more) |
Cellular Component | cytoplasm (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
akt1s1-201
(1)
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2379 |
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Browsers: NCBI, Ensembl, ZFIN |
akt1s1 Contained in: | [BAC] CH211-152F23 (order this) |
akt1s1 Encodes: | [EST] fb34a04, wz11024 |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:XM_687419 (1) | 2347 bp |
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Genomic | GenBank:BX005066 (1) | 172909 bp | |
Polypeptide | UniProtKB:E7EY34 (1) | 354 aa |
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Sequence Clusters | UniGene:104473 (1) |