Gene
dgat1a
- ID
- ZDB-GENE-030131-4600
- Name
- diacylglycerol O-acyltransferase 1a
- Symbol
- dgat1a Nomenclature History
- Previous Names
-
- dgat1
- DGAT1B (1)
- wu:fd36g11
- zgc:77691
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable diacylglycerol O-acyltransferase activity. Acts upstream of or within regulation of response to tumor cell. Predicted to be active in endoplasmic reticulum membrane. Is expressed in gut; liver; and muscle. Human ortholog(s) of this gene implicated in cardiomyopathy and congenital diarrhea 7 with exudative enteropathy. Orthologous to human DGAT1 (diacylglycerol O-acyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77691 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital diarrhea 7 with exudative enteropathy | Alliance | Diarrhea 7, protein-losing enteropathy type | 615863 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Diacylglycerol O-acyltransferase 1 | Membrane bound O-acyl transferase, MBOAT | Sterol O-acyltransferase, ACAT/DAG/ARE types |
|---|---|---|---|---|---|
| UniProtKB:Q6P3J0 | InterPro | 499 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dgat1a-201
(1)
|
Ensembl | 2,730 nt |
Interactions and Pathways
No data available
Plasmids