ZFIN ID: ZDB-GENE-030131-4600
Gene Name: diacylglycerol O-acyltransferase 1a
Gene Symbol: dgat1a    Nomenclature History

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Previous Names: dgat1, DGAT1B (1), wu:fd36g11, zgc:77691

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to localize to endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in cardiomyopathy and congenital diarrhea 7 with exudative enteropathy. Orthologous to human DGAT1 (diacylglycerol O-acyltransferase 1).
Genome Resources: Alliance (1),  Gene:325875 (1),  Ensembl(GRCz11):ENSDARG00000103503 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77691]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa39221 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43195 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dgat1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital diarrhea 7 with exudative enteropathy Alliance ?Diarrhea 7, protein-losing enteropathy type 615863
    DISEASE ASSOCIATED WITH dgat1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process triglyceride biosynthetic process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function diacylglycerol O-acyltransferase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dgat1a No data available
    MARKER RELATIONSHIPS
    dgat1a Contains: [SNP] rs3728946 (1), rs3728947 (1)
    dgat1a Encodes: [EST] fd36g11
    [cDNA] MGC:77691 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199730 (1) 2757 nt
    Polypeptide UniProtKB:Q6P3J0 (1) 499 aa
    Sequence Information (all 11)
    ORTHOLOGY for dgat1a ( Chr: 19 )
    CITATIONS (26)