ZFIN ID: ZDB-GENE-030131-4505
Gene Name: DEAH (Asp-Glu-Ala-His) box polypeptide 37
Gene Symbol: dhx37    Nomenclature History

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Previous Names: fd11d06, im:7151586, wu:fd11d06, zgc:158802

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Involved in positive regulation of mRNA splicing, via spliceosome. Predicted to localize to nucleolus. Orthologous to human DHX37 (DEAH-box helicase 37).
Genome Resources: Alliance (1),  Gene:100009635 (1),  Ensembl(GRCz11):ENSDARG00000062612 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7151586]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016406Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nig1 Point Mutation Unknown Missense
    sa12030 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa21183 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38663 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41108 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ws09771Tg Transgenic Insertion Intron 4 Unknown DNA
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dhx37 N/A 1
    MO2-dhx37 N/A 1
    MO3-dhx37 N/A 1
    MO4-dhx37 N/A 1
    DISEASE ASSOCIATED WITH dhx37 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    46, XY sex reversal 11 273250
    Neurodevelopmental disorder with brain anomalies and with or without vertebral or cardiac anomalies 618731
    DISEASE ASSOCIATED WITH dhx37 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of mRNA splicing, via spliceosome (more)
    Cellular Component nucleolus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dhx37-201 (1)    Ensembl 3714
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dhx37 No data available
    MARKER RELATIONSHIPS
    dhx37 Contained in: [BAC] DKEY-285C2 (1) (order this)
    dhx37 Encodes: [EST] fd11d06, IMAGE:7151586 (1)
    [cDNA] MGC:158802 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001083004 (1)
    Genomic GenBank:CU469504 (1) 138390 nt
    Select Tool
    Polypeptide UniProtKB:A0A0B6VLS4 (1) 1152 aa
    Sequence Information (all 23)
    ORTHOLOGY for dhx37 ( Chr: 8 )
    CITATIONS (28)