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ZIRC
ZFIN ID: ZDB-GENE-030131-4490
Gene Name: endothelial PAS domain protein 1a
Gene Symbol: epas1a
Sequence Ontology ID : SO:0001217

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Previous Names: hif-2aa (1), HIF2B (1), wu:fd10h02

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in Notch signaling pathway and hematopoietic stem cell differentiation. Predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns231 Small Deletion Exon 8 Frameshift, Premature Stop CRISPR
sa18133 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH epas1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial erythrocytosis 4 Erythrocytosis, familial, 4 611783
    DISEASE ASSOCIATED WITH epas1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hematopoietic stem cell differentiation (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA epas1a-202 (1) 5646
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM epas1a No data available
    MARKER RELATIONSHIPS
    epas1a Contained in: [BAC] DKEY-261G23 (1) (order this)
    epas1a Encodes: [EST] fd10h02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_690170 (1) 6207 bp
    Genomic GenBank:CR931998 (1) 144369 bp
    Select Tool
    Polypeptide UniProtKB:E7FAJ1 (1) 842 aa
    Sequence Clusters UniGene:83118 (1)
    Sequence Information (all 15)
    ORTHOLOGY for epas1a ( Chr: 12 )
    CITATIONS (28)