ZFIN ID: ZDB-GENE-030131-448
Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
Gene Symbol: ywhabl    Nomenclature History

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Previous Names: hm:zehn0976, iota2 (1), wu:fb33b01, zehn0976, zgc:77351

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have monooxygenase activity and protein domain specific binding activity. Predicted to be involved in oxidation-reduction process. Is expressed in head; nervous system; otic vesicle; post-vent region; and tail bud. Orthologous to human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) and YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta).
Genome Resources: Alliance (1),  Gene:321729 (1),  Ensembl(GRCz11):ENSDARG00000040287 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:73065]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6430 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ywhabl HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ywhabl VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Molecular Function monooxygenase activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Conserved_site IPR023409 14-3-3 protein, conserved site
Domain IPR023410 14-3-3 domain
Family IPR000308 14-3-3 protein
Homologous_superfamily IPR036815 14-3-3 domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ywhabl-201 (1)    Ensembl 1882
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ywhabl No data available
MARKER RELATIONSHIPS
ywhabl Contained in: [BAC] DKEY-56F14 (1) (order this), DKEY-79D12 (1) (order this)
ywhabl Encodes: [EST] fb33b01, zehn0976
[cDNA] MGC:73065 (1), MGC:77351 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_199562 (1) 1764 nt
Genomic GenBank:BX005256 (1) 199468 nt
Select Tool
Polypeptide UniProtKB:Q6P102 (1) 245 aa
Sequence Information (all 18)
ORTHOLOGY for ywhabl ( Chr: 16 )
CITATIONS (23)