ZFIN ID: ZDB-GENE-030131-4219
Gene Name: prolyl-tRNA synthetase 2, mitochondrial
Gene Symbol: pars2    Nomenclature History

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Previous Names: fc83e06, wu:fc83e06, zgc:77163 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have proline-tRNA ligase activity. Predicted to be involved in prolyl-tRNA aminoacylation. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human PARS2 (prolyl-tRNA synthetase 2, mitochondrial).
Genome Resources: Alliance (1),  Gene:325494 (1),  Ensembl(GRCz11):ENSDARG00000044404 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77163]
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pars2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Epileptic encephalopathy, early infantile, 75 618437
DISEASE ASSOCIATED WITH pars2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process prolyl-tRNA aminoacylation (more)
Cellular Component cytoplasm (more)
Molecular Function aminoacyl-tRNA ligase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pars2-201 (1)    Ensembl 1711
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pars2 No data available
MARKER RELATIONSHIPS
pars2 Contained in: [BAC] DKEY-218B7 (1) (order this)
pars2 Encodes: [EST] fc83e06
[cDNA] MGC:77163 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_205555 (1) 1719 nt
Genomic GenBank:BX088595 (1) 143341 nt
Select Tool
Polypeptide UniProtKB:F1QHZ4 (1) 477 aa
Sequence Information (all 10)
ORTHOLOGY for pars2 ( Chr: 6 )
CITATIONS (18)