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ZIRC
ZFIN ID: ZDB-GENE-030131-4153
Gene Name: ubiquitin specific peptidase 16
Gene Symbol: usp16    Nomenclature History

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Previous Names: wu:fc76b02, wu:fc76b08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have several functions, including cysteine-type peptidase activity; transcription coactivator activity; and zinc ion binding activity. Predicted to be involved in several processes, including histone H2A K63-linked deubiquitination; positive regulation of gene expression; and protein homotetramerization. Predicted to localize to the nucleus. Orthologous to human USP16 (ubiquitin specific peptidase 16).
Genome Resources: Alliance (1),  Gene:569700 (1), 
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7160401]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027649Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2796 Point Mutation Unknown Premature Stop ENU
    sa16288 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17060 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42615 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-usp16 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH usp16 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH usp16 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to DNA damage stimulus (more)
    Cellular Component nucleus (more)
    Molecular Function cysteine-type endopeptidase activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001607 (1)
  • InterPro:IPR013083 (1)
  • PROSITE:PS50271 (1)
  • Pfam:PF02148 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA usp16-201 (1)    Ensembl 3660
    usp16-202 (1)    Ensembl 746
    usp16-203 (1)    Ensembl 488
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM usp16 No data available
    MARKER RELATIONSHIPS
    usp16 Contained in: [BAC] DKEY-121N8 (1) (order this)
    usp16 Encodes: [EST] fc76b02, fc76b08 (1), IMAGE:7160401 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001146097 (1) 3660 bp
    Genomic GenBank:CR854897 (1) 185286 bp
    Select Tool
    Polypeptide UniProtKB:R4GEJ0 (1) 1438 aa
    Sequence Clusters UniGene:24329 (1)
    Sequence Information (all 29)
    ORTHOLOGY for usp16 ( Chr: 15 )
    CITATIONS (22)