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Gene

mark2a

ID
ZDB-GENE-030131-4145
Name
MAP/microtubule affinity-regulating kinase 2a
Symbol
mark2a Nomenclature History
Previous Names
  • fc75f05
  • si:dkey-175m17.8
  • wu:fc75f05 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in intracellular signal transduction and microtubule cytoskeleton organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in dendrite. Predicted to be active in cytoplasm. Orthologous to human MARK2 (microtubule affinity regulating kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mark2a Human Ortholog
No data available
Associated With mark2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001772 Kinase associated domain 1 (KA1)
Domain IPR015940 Ubiquitin-associated domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR028375 KA1 domain/Ssp2, C-terminal
Domain Details Per Protein
Protein Length KA1 domain/Ssp2, C-terminal Kinase associated domain 1 (KA1) Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Ubiquitin-associated domain
UniProtKB:A0A286Y815 756
UniProtKB:E9QGG3 109
UniProtKB:E9QHU0 736
UniProtKB:E7FBX4 759
UniProtKB:F1R380 139
UniProtKB:F1QMR7 140
UniProtKB:F1QDW7 242
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations