Gene

fbxo5

ID
ZDB-GENE-030131-4027
Name
F-box protein 5
Symbol
fbxo5 Nomenclature History
Previous Names
  • emi1 (1)
  • fc65h02
  • harpy (1)
  • hrp (1)
  • rca1 (1)
  • wu:fc65h02
  • wu:fe06e07
  • wu:fz79f03
  • zgc:136397
  • zgc:158541
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Is predicted to enable ubiquitin ligase inhibitor activity. Involved in negative regulation of meiotic nuclear division; negative regulation of ubiquitin protein ligase activity; and regulation of mitotic nuclear division. Acts upstream of or within several processes, including hemopoiesis; mitotic cytokinesis; and negative regulation of mitotic nuclear division. Predicted to be located in cytoplasm and spindle. Is expressed in several structures, including alar plate midbrain region; blood; nervous system; optic vesicle; and segmental plate. Orthologous to human FBXO5 (F-box protein 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
24 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbxo5 Human Ortholog
No data available
Associated With fbxo5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Domain IPR002867 IBR domain
Domain IPR044064 Zinc finger ZBR-type domain
Homologous_superfamily IPR036047 F-box-like domain superfamily
Domain Details Per Protein
Protein Length F-box domain F-box-like domain superfamily IBR domain Zinc finger ZBR-type domain
UniProtKB:F1QTH3 116
UniProtKB:A3KP15 384
UniProtKB:Q0V967 384
UniProtKB:F1QJI8 384
UniProtKB:Q567N7 347
UniProtKB:B5DDG9 384
UniProtKB:A4VAL0 170
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-fbxo5 polyclonal Rabbit
Life Technologies (Invitrogen)
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations