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ZIRC
ZFIN ID: ZDB-GENE-030131-3844
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Gene Name: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Gene Symbol: uchl1
Sequence Ontology ID : SO:0001217

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Previous Names: cb358 (1), wu:fc55h08

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in protein deubiquitination. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene  ...
GENE EXPRESSION
All Expression Data: 10 figures from 5 publications
Directly Submitted Expression Data: 5 figures (39 images) from Thisse et al., 2001 [cb358]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38261 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • zko428a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
    • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH uchl1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Spastic paraplegia 79, autosomal recessive 615491
    {?Parkinson disease 5, susceptibility to} 613643
    DISEASE ASSOCIATED WITH uchl1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein deubiquitination (more)
    Cellular Component cytoplasm (more)
    Molecular Function cysteine-type peptidase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001578 (1)
  • InterPro:IPR030297 (1)
  • InterPro:IPR036959 (1)
  • InterPro:IPR038765 (1)
  • PROSITE:PS00140 (1)
  • Pfam:PF01088 (1)
  • EC:3.4.19.12 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA uchl1-002 (1) 338
    Select Tool
    mRNA uchl1-201 (1) 1490
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM uchl1 No data available
    MARKER RELATIONSHIPS
    uchl1 Contained in: [BAC] CH211-240P12 (1) (order this)
    [Fosmid] ZFOS-2069A7 (1)
    uchl1 Encodes: [EST] cb358 (1), fc55h08
    [cDNA] MGC:56535 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201477 (1) 1118 bp
    Select Tool
    Genomic GenBank:CR376846 (1) 145408 bp
    Select Tool
    Polypeptide UniProtKB:Q6YI49 (1) 218 aa
    Select Tool
    Sequence Clusters UniGene:8724 (1)
    Sequence Information (all 16)
    OTHER uchl1 GENE PAGES
  • Alliance (1)
  • Gene:325119 (1)
  • VEGA:OTTDARG00000030233 (1)
  • Ensembl(GRCz11):ENSDARG00000026871 (2)
    • ORTHOLOGY for uchl1 ( Chr: 1 )
    CITATIONS (33)