ZFIN ID: ZDB-GENE-030131-3776
Gene Name: phosphatase and tensin homolog A
Gene Symbol: ptena
Sequence Ontology ID : SO:0000704

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Previous Names: wu:fc52g04, zgc:73086

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 5 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:73086]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu1864 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013071Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12727 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39161 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa42927 Point Mutation Unknown Premature Stop ENU
    Targeting reagents:
    PHENOTYPE
    Data: 6 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH ptena HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cowden disease Cowden syndrome 1 158350
    Lhermitte-Duclos syndrome 158350
    macrocephaly-autism syndrome Macrocephaly/autism syndrome 605309
    prostate cancer {Prostate cancer, somatic} 176807
    VACTERL association VATER association with macrocephaly and ventriculomegaly 276950
    {Glioma susceptibility 2} 613028
    {Meningioma} 607174
    DISEASE ASSOCIATED WITH ptena VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphatidylinositol dephosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function lipid phosphatase activity (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000340 (1)
  • InterPro:IPR003595 (1)
  • InterPro:IPR014020 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR017361 (1)
  • InterPro:IPR029021 (1)
  • InterPro:IPR029023 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS51181 (1)
  • PROSITE:PS51182 (1)
  • Pfam:PF00782 (1)
  • Pfam:PF10409 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptena-001 (1) 2993
    ptena-002 (1) 1341
    ncRNA ptena-003 (1) 658
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ptena No data available
    MARKER RELATIONSHIPS
    ptenaContained in: [BAC] CH211-243K10 (1) (order this)
    ptenaEncodes: [EST] fc52g04
    [cDNA] MGC:73086 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200708 (1) 1646bp
    Genomic GenBank:CR384057 (1) 154493bp
    Select Tool
    Polypeptide UniProtKB:E7FC59 (1) 467aa
    Sequence Clusters UniGene:76854 (1)
    Sequence Information (all 26)
    OTHER ptena GENE PAGES
  • Alliance (1)
  • Gene:794088 (1)
  • VEGA:OTTDARG00000020224 (1)
  • ORTHOLOGY for ptena (Chr: 17)
    CITATIONS (46)