Gene

zfyve26

ID
ZDB-GENE-030131-3286
Name
zinc finger, FYVE domain containing 26
Symbol
zfyve26 Nomenclature History
Previous Names
  • spastizin (1)
  • suf
  • wu:fc33a03
  • zspg15 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have phosphatidylinositol-3-phosphate binding activity. Involved in axonogenesis and oocyte development. Predicted to localize to centrosome and midbody. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 15. Is expressed in fertilized egg; nervous system; oocyte; and somatic cell. Orthologous to human ZFYVE26 (zinc finger FYVE-type containing 26).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With zfyve26 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 15 Alliance Spastic paraplegia 15, autosomal recessive 270700
Associated With zfyve26 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000306 FYVE zinc finger
Domain IPR017455 Zinc finger, FYVE-related
Family IPR028730 Zinc finger FYVE domain-containing protein 26
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length FYVE zinc finger Zinc finger FYVE domain-containing protein 26 Zinc finger, FYVE/PHD-type Zinc finger, FYVE-related Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A067YRV0 2269
UniProtKB:F6NK88 2552
UniProtKB:F1Q533 2551
UniProtKB:A0A067YRN8 2552
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations