ZFIN ID: ZDB-GENE-030131-3238
Gene Name: poly(A) binding protein, cytoplasmic 1a
Gene Symbol: pabpc1a    Nomenclature History

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Previous Names: pabpc1, wu:fb16a02, wu:fc31e01, wu:fi19b08, wu:fj12d09, wu:fj61f06, zgc:109879

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Involved in heart development. Predicted to localize to several cellular components, including cytoplasmic stress granule; cytosol; and ribonucleoprotein complex. Is expressed in several structures, including central nervous system; digestive system; eye; pectoral fin bud; and ventral mesenchyme. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1).
Genome Resources: Alliance (1),  Gene:606498 (1),  Ensembl(GRCz11):ENSDARG00000017219 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi3202bTg Transgenic Insertion Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027788Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39135 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pabpc1a N/A 2
    MO2-pabpc1a N/A 1
    DISEASE ASSOCIATED WITH pabpc1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pabpc1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart development (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pabpc1a-201 (1)    Ensembl 2554
    pabpc1a-202 (1)    Ensembl 2033
    ncRNA pabpc1a-003 (1) 539
    pabpc1a-004 (1) 660
    pabpc1a-005 (1) 330
    pabpc1a-006 (1) 747
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pabpc1a No data available
    MARKER RELATIONSHIPS
    pabpc1a Contained in: [Fosmid] CH1073-73G20 (1)
    pabpc1a Encodes: [EST] fb16a02 (order this), fi19b08, fj12d09, fj61f06, IMAGE:7151399 (1)
    [cDNA] MGC:109879 (1)
    pabpc1a Has Artifact: [EST] fb07f04, fc31e01
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001031676 (1) 2412 nt
    Genomic GenBank:CU855877 (1) 30279 nt
    Select Tool
    Polypeptide UniProtKB:F1QB54 (1) 634 aa
    Sequence Information (all 23)
    ORTHOLOGY for pabpc1a ( Chr: 16 )
    CITATIONS (48)