ZFIN ID: ZDB-GENE-030131-3217
Gene Name: apolipoprotein L, 1
Gene Symbol: apol1
Sequence Ontology ID : SO:0000704

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Previous Names: si:rp71-1g18.12, wu:fa95b12 (1), wu:fc30h04 (1)

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have lipid binding activity; involved in glomerular filtration, glomerular visceral epithelial cell development, and pronephric glomerulus morphogenesis; predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32975 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 9 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH apol1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {End-stage renal disease, nondiabetic, susceptibility to} 612551
    {Glomerulosclerosis, focal segmental, 4, susceptibility to} 612551
    DISEASE ASSOCIATED WITH apol1 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    kidney disease AB/EKW + MO2-apol1 standard conditions Anderson et al., 2015
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glomerular filtration (more)
    Cellular Component extracellular region (more)
    Molecular Function lipid binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR008405 (1)
  • Pfam:PF05461 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apol1-001 (1) 2166
    ncRNA apol1-002 (1) 767
    apol1-202 (1) 725
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM apol1 No data available
    MARKER RELATIONSHIPS
    apol1Contained in: [BAC] DKEY-75G22 (1) (order this), RP71-1G18 (order this)
    apol1Encodes: [EST] fa95b12, fc30h04
    [cDNA] MGC:136610 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030138 (1) 1740bp
    Genomic GenBank:AL627248 143586bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IKX7 (1) 326aa
    Sequence Clusters UniGene:5195 (1)
    Sequence Information (all 21)
    OTHER apol1 GENE PAGES
  • Alliance (1)
  • Gene:560340 (1)
  • VEGA:OTTDARG00000034694 (1)
  • ORTHOLOGY for apol1 (Chr: 2)
    CITATIONS (17)