Gene

ubiad1

ID
ZDB-GENE-030131-3205
Name
UbiA prenyltransferase domain containing 1
Symbol
ubiad1 Nomenclature History
Previous Names
  • bar
  • barolo (1)
  • unm t31131
  • unm_t31131
  • wu:fc30e12
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Enables antioxidant activity; nitric-oxide synthase activity; and prenyltransferase activity. Involved in endothelial cell development; menaquinone biosynthetic process; and vitamin K biosynthetic process. Acts upstream of or within cellular response to fluid shear stress; circulatory system development; and ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate. Located in Golgi apparatus. Is integral component of Golgi membrane. Is expressed in head; heart; and heart tube. Human ortholog(s) of this gene implicated in Schnyder corneal dystrophy. Orthologous to human UBIAD1 (UbiA prenyltransferase domain containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ubiad1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Schnyder corneal dystrophy Alliance Corneal dystrophy, Schnyder type 121800
Associated With ubiad1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000537 UbiA prenyltransferase family
Family IPR026046 UbiA prenyltransferase domain containing protein 1
Domain Details Per Protein
Protein Length UbiA prenyltransferase domain containing protein 1 UbiA prenyltransferase family
UniProtKB:E7FB98 336
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ubiad1 monoclonal Mouse
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations