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Gene

bptf

ID
ZDB-GENE-030131-3200
Name
bromodomain PHD finger transcription factor
Symbol
bptf Nomenclature History
Previous Names
  • fc30e02
  • fc32a05
  • wu:fb71f11
  • wu:fc30e02
  • wu:fc32a05
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including cranial skeletal system development; neural plate anterior/posterior regionalization; and nucleosome positioning. Predicted to be located in nucleus. Predicted to be part of NURF complex. Is expressed in head. Orthologous to human BPTF (bromodomain PHD finger transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Ma et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bptf Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies 617755
Associated With bptf Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018359 Bromodomain, conserved site
Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
Domain IPR001487 Bromodomain
Domain IPR001510 Zinc finger, PARP-type
Domain IPR001965 Zinc finger, PHD-type
Domain IPR018501 DDT domain
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR028941 WHIM2 domain
Family IPR038028 Nucleosome-remodeling factor subunit BPTF
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR036427 Bromodomain-like superfamily
Domain Details Per Protein
Protein Length Bromodomain Bromodomain, conserved site Bromodomain-like superfamily DDT domain Nucleosome-remodeling factor subunit BPTF WHIM2 domain Zinc finger, FYVE/PHD-type Zinc finger, PARP-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, PHD-type, conserved site Zinc finger, RING/FYVE/PHD-type
UniProtKB:E7F366 2899
UniProtKB:A0A2R8Q3B9 2804
UniProtKB:X1WDW8 2806
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bptf polyclonal Rabbit
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations