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Gene

psmc6

ID
ZDB-GENE-030131-304
Name
proteasome 26S subunit, ATPase 6
Symbol
psmc6 Nomenclature History
Previous Names
  • fb20g04
  • wu:fb20g04
  • wu:fc85c10
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable ATP binding activity and peptidase activity. Predicted to be involved in positive regulation of RNA polymerase II transcription preinitiation complex assembly and ubiquitin-dependent ERAD pathway. Predicted to act upstream of or within protein catabolic process and proteolysis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cytosolic proteasome complex and proteasome regulatory particle, base subcomplex. Orthologous to human PSMC6 (proteasome 26S subunit, ATPase 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With psmc6 Human Ortholog
No data available
Associated With psmc6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003960 ATPase, AAA-type, conserved site
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Domain IPR032501 Proteasomal ATPase OB C-terminal domain
Domain IPR041569 AAA ATPase, AAA+ lid domain
Family IPR005937 26S proteasome regulatory subunit P45-like
Family IPR035263 26S proteasome regulatory subunit 10B
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit P45-like AAA ATPase, AAA+ lid domain AAA+ ATPase domain ATPase, AAA-type, conserved site ATPase, AAA-type, core P-loop containing nucleoside triphosphate hydrolase Proteasomal ATPase OB C-terminal domain
UniProtKB:Q1LUG7 269
UniProtKB:R4GEZ7 182
UniProtKB:Q6DRD2 389
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations