ZFIN ID: ZDB-GENE-030131-2579
Gene Name: karyopherin (importin) beta 1
Gene Symbol: kpnb1    Nomenclature History

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Previous Names: wu:fc12b10, zgc:123184

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to localize to cytoplasm and nucleus. Is expressed in digestive system; nervous system; and neural keel. Orthologous to human KPNB1 (karyopherin subunit beta 1).
Genome Resources: Alliance (1),  Gene:570700 (1),  Ensembl(GRCz11):ENSDARG00000104889 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 10 figures (30 images) from Rauch et al., 2003 [cegs2523]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-kpnb1 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH kpnb1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH kpnb1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular protein transport (more)
Cellular Component nucleus (more)
Molecular Function Ran GTPase binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA kpnb1-201 (1)    Ensembl 3774
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM kpnb1 No data available
MARKER RELATIONSHIPS
kpnb1 Contained in: [Fosmid] CH1073-205C8 (1)
kpnb1 Encodes: [EST] cegs2523 (1) (order this), fc12b10
[cDNA] MGC:123184 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001037702 (1) 3795 nt
Genomic GenBank:CU929079 (1) 25159 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IMZ8 (1) 876 aa
Sequence Information (all 22)
ORTHOLOGY for kpnb1 ( Chr: 19 )
CITATIONS (24)