ZFIN ID: ZDB-GENE-030131-2455
Gene Name: syntaxin 4
Gene Symbol: stx4    Nomenclature History

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Previous Names: si:dkey-220f10.3, wu:fc08c10, zgc:56272 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to localize to several cellular components, including the SNARE complex; presynaptic active zone membrane; and synaptic vesicle. Orthologous to human STX4 (syntaxin 4).
Genome Resources: Alliance (1),  Gene:323735 (1),  Ensembl(GRCz11):ENSDARG00000052518 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6901547]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH stx4 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH stx4 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular protein transport (more)
Cellular Component integral component of membrane (more)
Molecular Function SNAP receptor activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Conserved_site IPR006012 Syntaxin/epimorphin, conserved site
Domain IPR000727 Target SNARE coiled-coil homology domain
Domain IPR006011 Syntaxin, N-terminal domain
Homologous_superfamily IPR010989 SNARE
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA stx4-201 (1)    Ensembl 2055
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM stx4 No data available
MARKER RELATIONSHIPS
stx4 Contained in: [BAC] DKEY-220F10 (1) (order this)
stx4 Encodes: [EST] fc08c10, IMAGE:6901547 (1)
[cDNA] MGC:56272 (1), MGC:174104 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200221 (1) 1926 nt
Genomic GenBank:CR926135 (1) 73888 nt
Select Tool
Polypeptide UniProtKB:A0A2R8RWS3 (1) 298 aa
Sequence Information (all 19)
ORTHOLOGY for stx4 ( Chr: 12 )
CITATIONS (21)