ZFIN ID: ZDB-GENE-030131-2100
Gene Name: hatching enzyme 1, tandem dupliate 2
Gene Symbol: he1.2    Nomenclature History

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Previous Names: he1b (1), Zh-1 (1), ZHce1 (1), fb96f07, si:ch211-246m6.8, wu:fb96f07, zebrafish HCE homologue 1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Exhibits metallopeptidase activity. Involved in hatching and proteolysis. Is expressed in hatching gland cell. Orthologous to human ASTL (astacin like metalloendopeptidase).
Genome Resources: Alliance (1),  Gene:407971 (1), 
GENE EXPRESSION
All Expression Data: Fig. 1 from Sano et al., 2008
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH he1.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH he1.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hatching (more)
Molecular Function metallopeptidase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA he1.2-201 (1)    Ensembl 980
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM he1.2 No data available
MARKER RELATIONSHIPS
he1.2 Contained in: [BAC] CH211-246M6 (1)
he1.2 Encodes: [cDNA] MGC:162370 (1)
he1.2 Has Artifact: [EST] fb96f07
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213635 (1) 1012 nt
Genomic GenBank:BX649296 (1) 175492 nt
Select Tool
Polypeptide UniProtKB:Q1LW00 (1) 263 aa
Sequence Information (all 15)
ORTHOLOGY for he1.2 ( Chr: 22 )
CITATIONS (29)