ZFIN ID: ZDB-GENE-030131-1936
Gene Name: LIM and SH3 protein 1
Gene Symbol: lasp1    Nomenclature History

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Previous Names: fb92f05, wu:fb92f05, zgc:77542

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to localize to focal adhesion. Orthologous to human LASP1 (LIM and SH3 protein 1).
Genome Resources: Alliance (1),  Gene:323216 (1),  Ensembl(GRCz11):ENSDARG00000057867 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77542]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028860Tg Transgenic Insertion Unknown Unknown DNA
sa33119 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tpl20Gt Transgenic Insertion Unknown Unknown DNA
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lasp1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lasp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component focal adhesion (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lasp1-201 (1)    Ensembl 2330
    lasp1-202 (1)    Ensembl 1970
    ncRNA lasp1-003 (1)    Ensembl 623
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lasp1 No data available
    MARKER RELATIONSHIPS
    lasp1 Contained in: [BAC] DKEY-81L17 (1) (order this)
    lasp1 Encodes: [EST] fb92f05
    [cDNA] MGC:77542 (1), MGC:174409 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212636 (1) 2140 nt
    Genomic GenBank:CR387933 (1) 182618 nt
    Select Tool
    Polypeptide UniProtKB:Q7SYA6 (1) 240 aa
    Sequence Information (all 18)
    ORTHOLOGY for lasp1 ( Chr: 3 )
    CITATIONS (27)